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探讨血液流变学在评价大容量全肺灌洗（WLL）治疗矽肺疗效中的应用。对30例实施大容量全肺灌洗治疗的矽肺患者作了灌洗前后血液流变学的动态观察及肺功能测定、血气分析。结果：经大容量全肺灌洗治疗的矽肺患者由于肺通气功能的改善及动脉血氧分压（PaO2）的提高，其高粘滞血症、红细胞聚集、红细胞变形异常、Casson屈服应力增高状态有明显改善，各项指标均趋于正常。血液流变学的各项检查在评价大容量全肺灌洗治疗矽肺的疗效中具有重要作用。
To investigate the application of hemorheology in the evaluation of the efficacy of large-volume whole lung lavage (WLL) in the treatment of silicosis. Thirty patients with silicosis who were treated with large-volume all-pulmonary irrigation were given dynamic changes of hemorheology, pulmonary function test and blood gas analysis before and after lavage. Results: The patients with silicosis treated by high-capacity whole lung lavage showed hyperviscosity, erythrocyte aggregation, abnormal erythrocyte deformation and increased Casss stress state due to the improvement of pulmonary ventilation and the increase of arterial oxygen tension (PaO2) There was a marked improvement, with all the indicators getting normal. Various tests of hemorheology play an important role in evaluating the efficacy of large-volume whole-cell lavage in the treatment of silicosis.