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电离辐射作用于机体可引起生物大分子的激发和电离 ,造成ＤＮＡ损伤 ,染色体畸变率增加。染色体畸变已作为评价电离辐射生物学效应的参考指标。我们应用单细胞凝胶电泳 (ＳＣＧＥ)技术对放射人员外周血淋巴细胞ＤＮＡ损伤进行了检测 ,以探讨简易、敏感的评价电离辐射生物学效应
Ionizing radiation on the body can cause the excitation and ionization of biological macromolecules, resulting in DNA damage, increased chromosome aberration rate. Chromosome aberration has been used as a reference to evaluate the biological effects of ionizing radiation. We used single cell gel electrophoresis (SCGE) technology to detect DNA damage in peripheral blood lymphocytes of radiologists to investigate simple and sensitive biological effects of ionizing radiation