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目的探讨阿司匹林、克罗米芬、人绒毛膜促性腺激素联合治疗不孕症的临床效果。方法选择2014年2月~2015年9月我站136例不孕症育龄妇女,按随机数表法分为单一组(n=68)和联合组(n=68),单一组单纯采用克罗米芬治疗,联合组采用阿司匹林+克罗米芬+人绒毛膜促性腺激素联合治疗,比较两组临床疗效。结果联合组临床总有效率92.65%,显著高于单一组72.06%(P<0.05);联合组排卵率、妊娠率均显著高于单一组,差异具有统计学意义(P<0.05);联合组患者子宫内膜厚度、宫颈黏液评分均明显优于单一组(P<0.05)。结论阿司匹林、克罗米芬、人绒毛膜促性腺激素联合治疗不孕症效果显著,可有效增加患者子宫内膜厚度,利于其早日受孕。
Objective To investigate the clinical effects of aspirin, clomiphene citrate and human chorionic gonadotropin in the treatment of infertility. Methods From February 2014 to September 2015, 136 infertility women of childbearing age at our station were divided into single group (n = 68) and combination group (n = 68) according to random number table. Single group were treated with clomiphene In the treatment group, aspirin + clomiphene + human chorionic gonadotropin was used in the combination group, and the clinical efficacy was compared between the two groups. Results The total clinical effective rate in the combined group was 92.65%, significantly higher than that in the single group (72.06%, P <0.05). The ovulation rate and pregnancy rate in the combined group were significantly higher than those in the single group (P <0.05) Patients with endometrial thickness, cervical mucus scores were significantly better than the single group (P <0.05). Conclusion Aspirin, clomiphene and human chorionic gonadotropin combined treatment of infertility effect is significant, which can effectively increase the thickness of the endometrium in patients with early pregnancy benefit.