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目的探讨甲型H1N1流感患者的临床特点及其转归。方法对11例甲型H1N1流感患者进行隔离治疗,分析其流行病学、临床表现、实验室检查、治疗效果及临床转归等方面资料。结果甲型H1N1流感好发于年轻人,发热、咳嗽及咽部不适为主要临床症状,部分患者出现白细胞减少及低钾血症,早期应用抗病毒治疗后,平均1.5d后体温正常,平均6.6d后咽拭子病毒转阴,8.3d痊愈;治疗中未见明显药物不良反应出现。结论甲型H1N1流感轻症患者早期抗病毒治疗有助于缩短病程,使用奥司他韦无论是进口的达菲,还是我国的军科奥韦治疗甲型H1N1流感均是安全、有效的。
Objective To investigate the clinical characteristics and prognosis of patients with influenza A (H1N1). Methods 11 cases of influenza A (H1N1) were treated with isolation and analysis of epidemiology, clinical manifestations, laboratory tests, treatment effects and clinical outcomes. Results Influenza A (H1N1) influenza developed mainly in young people. Fever, cough and pharyngeal discomfort were the main clinical symptoms. Some patients had leukopenia and hypokalemia. After antiviral therapy, the average body temperature was 1.5d After throat swab virus d, 8.3d heal; no obvious adverse drug reactions appear in the treatment. Conclusion Influenza A H1N1 influenza patients with mild early anti-viral therapy can help reduce the duration of the use of oseltamivir, whether imported Tamiflu, or our military Overal H1N1 flu treatment are safe and effective.