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目的研究和胃口服液对动物胃肠运动功能的影响。方法采用小鼠整体胃排空试验、小肠推进试验和家兔离休十二指肠运动试验测定和胃口服液对正常小鼠胃排空、小肠推进运动及家兔离体胸管自发肠活动、药物引起的肠收缩和肠抑制的影响。结果和胃口服液对正常小鼠胃排空有增加趋势;对正常小鼠的小肠运动有明显的推进作用;对高体免十二指肠的正常脉管运动亦呈一定的兴奋作用,对乙酸胆碱、组股、BaC12引起的兴奋状态的肠肌运动有抑制的能力,对肾上腺素引起的抑制状态的肠肌运动有兴奋功效。结论和胃口服液对实验动物的正常胃肠运动有一定的促进作用;对异常脉管运动有良好的双向调节作用。
Objective To study the effect of Weihe oral liquid on gastrointestinal motility in animals. Methods Gastric emptying, small intestine advancing exercise and spontaneous intestinal activity of isolated rabbit thoracic ducts in normal mice were determined by whole gastric emptying test, small intestine advancing test and rabbit resuscitation duodenal exercise test. Drug-induced bowel contractions and bowel suppression effects. Results Hewei Oral Liquid had an increased tendency to gastric emptying in normal mice; it had a significant advancing effect on the small intestine movement in normal mice; and also had a certain excitatory effect on the normal vasculature in the duodenum-free duodenum. Acetylcholine, group strands, and BaC12 have the ability to inhibit intestinal muscle movement in the excited state, and have excitatory effects on the intestinal muscle movement caused by epinephrine. Conclusion Hewei oral liquid has a certain promoting effect on the normal gastrointestinal motility of experimental animals; it has a good two-way adjustment effect on abnormal vascular motility.