患者女,28岁,因尿频,尿痛,排尿困难,伴下腹痛,来我院就诊。经相关检查诊断为淋病。既往无药物过敏史,常规青霉素皮试阴性。给予注射用头孢噻肟钠4g,加入5％葡萄糖氯化钠注射液250ml静滴。输入约10min后,患者诉心慌,气短,全身皮肤发痒,上肢、胸、腹部出现荨麻疹,随之意识丧失。查体: Female patient, 28 years old, because of frequent urination, dysuria, dysuria, with abdominal pain, to our hospital. The relevant examination diagnosed as gonorrhea. Past history of drug allergy, routine penicillin skin test negative. Give injection of cefotaxime sodium 4g, add 5% glucose and sodium chloride injection 250ml intravenous infusion. Enter about 10min, the patient complained of panic, shortness of breath, itchy skin, upper limbs, chest, abdomen, urticaria, followed by loss of consciousness. Physical examination: