论文部分内容阅读
异烟肼分子结构中含有肼类功能团(-NHNH_2)称配位体,遇到铁、镁、铝等金属离子,由于两者间的相互作用,产生螫合反应,生成异烟肼——铁、镁、铝等螫合物,使异烟肼生物效应降低。然而,中成药牛黄解毒片、陈香露白露片、当归浸膏片、胃舒宁片、复方五味子片等能否与异烟肼同时并服呢?让我们先剖析一下各种药物所含的成分就可以清楚了。牛黄解毒片含牛黄0.005g、桔梗0.1g、甘草0.05g、黄芩0.15g、大黄
The molecular structure of isoniazid contains ligands of the hydrazine functional group (-NHNH2). It encounters metal ions such as iron, magnesium and aluminum. Due to the interaction between the two, it generates a chelation reaction and generates isoniazid. Iron, magnesium, aluminum and other complexes reduce the biological effects of isoniazid. However, whether proprietary Chinese medicines such as Niuhuang Jiedu Tablets, Chenxianglu Bailu Tablets, Angelica Extract Tablets, Weishuning Tablets, and Compound Schisandra Tablets can be combined with isoniazid simultaneously? Let us first analyze the ingredients contained in various medicines. Can be clear. Niuhuangjiedu Tablets Containing Niuhuang 0.005g, Platycodon radiata 0.1g, Glycyrrhiza uralensis 0.05g, Radix Astragali 0.15g, Rhubarb