流行病学调查提示妊娠女性使用抗精神病药的频率在不断增加。然而，孕期服用抗精神病药的安全性证据缺乏，孕期能否使用抗精神病药仍然存有争议。我国国家药品监督管理局及美国食品药品监督管理局等至今没有批准任何抗精神病药可以在孕期使用，抗精神病药的胚胎毒性不能排除。目前有限的临床研究和基础研究证据提示孕期服用抗精神病药可能对子代远期神经发育具有潜在不良影响。“,”Epidemiological studies indicate that the use of antipsychotics in pregnant women has progressively increased. However, the safety evidence about antipsychotics use during pregnancy is scarce. The plausibility of antipsychotics use during pregnancy remains controversial. No antipsychotic has been approved for use during pregnancy by the National Medical Products Administration and Food and Drug Administration. Embryotoxicity of antipsychotics cannot be excluded. Currently, limited clinical and basic research evidence suggests that the use of antipsychotic drugs during pregnancy may have potential adverse effects on the long-term neurodevelopment of offspring.