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目的探讨新疆乌鲁木齐地区体检人群肥胖的发病率及与肥胖相关的代谢指标。方法回顾性分析自2013年至2014年新疆医科大学第一附属医院18 926例体检者的体质量指数(BMI)、血糖、血脂、血压、血尿酸、肌酐、天门冬酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、肝脏B超的结果,并对汉族、回族、维吾尔族、哈萨克族、蒙古族5个民族人群肥胖的患病率进行统计分析。结果 18 926例体检者中肥胖总患病率为19.95%,其中男性为13.53%,高于女性的6.41%(χ2=220.982,P=0.000)。汉族、回族、维吾尔族、哈萨克族、蒙古族的肥胖患病率依次为12.12%、21.46%、29.32%、21.67%、20.84%,维族肥胖患者检出率最高,汉族最低,不同民族间肥胖检出率比较差异有统计学意义(χ2=435.751,P=0.000)。各民族间的各代谢参数比较,差异均有统计学意义(P<0.05)。多元线性回归分析显示,肥胖对空腹血糖(FPG)、三酰甘油(TG)、总胆固醇(TC)无影响(P>0.05);高密度脂蛋白胆固醇(HDL-C)、AST、肌酐水平与肥胖程度呈负相关(t=-15.537、-4.684、-2.739,P=0.000、0.000、0.006),脂肪肝、年龄、收缩压、ALT、尿酸、低密度脂蛋白胆固醇(LDL-C)、舒张压水平与肥胖呈正相关(P<0.05)。结论新疆乌鲁木齐体检人群肥胖患病率存在种族差异,肥胖已成为该地区严重的社会公共问题。
Objective To investigate the prevalence of obesity and metabolic indices related to obesity among medical examination population in Urumqi, Xinjiang. Methods The body mass index (BMI), blood glucose, blood lipid, blood pressure, serum uric acid, creatinine and aspartate aminotransferase (AST) in 18 926 subjects from the First Affiliated Hospital of Xinjiang Medical University from 2013 to 2014 were retrospectively analyzed. , Alanine aminotransferase (ALT) and liver B-ultrasound, and analyzed the prevalence of obesity among five ethnic groups in Han, Hui, Uygur, Kazak and Mongol nationalities. Results The total prevalence of obesity in 18 926 subjects was 19.95%, with 13.53% in males and 6.41% in females (χ2 = 220.982, P = 0.000). The prevalence rates of obesity among Han, Hui, Uygur, Kazak and Mongolians were 12.12%, 21.46%, 29.32%, 21.67% and 20.84%, respectively. The prevalence of obesity in Uighur was the highest, lowest among Han nationalities, The difference was statistically significant (χ2 = 435.751, P = 0.000). The metabolic parameters of all ethnic groups were compared, the differences were statistically significant (P <0.05). Multivariate linear regression analysis showed that obesity had no effect on fasting plasma glucose (FPG), triglyceride (TG) and total cholesterol (TC) (P> 0.05); HDL-C, (T = -15.537, -4.684, -2.739, P = 0.000,0.000,0.006), fatty liver, age, systolic blood pressure, ALT, uric acid, low density lipoprotein cholesterol (LDL-C) Pressure levels and obesity were positively correlated (P <0.05). Conclusion There are racial differences in the prevalence of obesity in Urumqi, Xinjiang. Obesity has become a serious social and public problem in the region.