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为了解子宫内膜异位症患者腹腔巨噬细胞活性变化,建立了应用Frua-2测定人腹腔巨噬细胞胞浆游离钙浓度([Ca2+]i)的方法。结果显示,正常盆腔患者腹腔巨噬细胞[Ca2+]i为(100.32±5.69)nmol/L,而子宫内膜异位症患者腹腔巨噬细胞较正常盆腔者显著升高。表明子宫内膜异位症患者腹腔巨噬细胞活性增强与其[Ca2+]i增高有关
In order to understand the changes of peritoneal macrophage activity in patients with endometriosis, the method of Frua-2 determination of cytosolic free calcium concentration in human peritoneal macrophages ([Ca2 +] i) was established. The results showed that [Ca2 +] i in peritoneal macrophages of normal pelvic patients was (100.32 ± 5.69) nmol / L, while that of peritoneal macrophages in patients with endometriosis was significantly higher than that in normal pelvis. That endometriosis in patients with peritoneal macrophage activity increased with its [Ca2] i increased