肝硬化患者出现神经系统症状与体征可见于下列3种情况:(1)肝昏迷,有明显门,体侧枝循环存在者,常出现一时性肌张力增高、腱反射亢进等;(2)肝豆状核变性,由于基底神经节变性而出现锥体外系的体征,(3)肝硬化伴持续的脑脊髓病变。后者极为少见。Zieve L(Ann Int Med 53[1]):53,1960)首先报告2例肝硬化伴脊髓病,皆于门腔静脉吻合术后发病,并经尸检证明为脊髓锥体束脱髓鞘病变。国内仅 Patients with cirrhosis of the nervous system symptoms and signs can be found in the following three kinds of situations: (1) hepatic coma, there are obvious doors, the body of the branches and branches exist, often appear transient hypotonia, tendon hyperreflexia; (2) Nucleus degeneration, extrapyramidal signs due to degeneration of basal ganglia, (3) Cirrhosis with persistent cerebrospinal cord lesions. The latter is extremely rare. Zieve L (Ann Int Med 53 [1]): 53, 1960) first reported 2 cases of cirrhosis with myelopathy, all of which developed after anastomosis of the portal vein and were proved by autopsy to be myelinated demyelinating lesions of the spinal cord. Domestic only