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一、不合理用药状况所查9所医院共1517例住院病历,98.3%使用过2种以上药物,用单种药物者占1.7%。在24小时内用2~5种药物者占48.91%,用6~10种药物者占39.55%。并用药物的病例约40%有有益相互作用,20%有不良的相互作用,其余的25%不存在有意义的药物相互作用。200例住院死亡病例中,直接或不能排除与药源性死亡有关者22例(占11%),其中绝大部分用药问题并非不可克服的治疗矛盾或不可避免的药物反应,而系违反用药禁忌症和存在不良的药物相互作用。药源性死亡病例,其原有疾病的病情绝大多数比较危急而且又是目前尚无特殊治疗办法的重症,如脑血管病、冠心病、显著肝肾功能不全、肺心病及癌症等。虽其治愈希望不大,但用药失误而促进死亡亦非罕见,这在医德与医术上都是绝不允许的。患者原有疾病轻微而且完全可以治愈,而用药错误造成死亡则属罕见,据报道仅占用药者的万分
First, irrational drug use The investigation of 9 hospitals in a total of 1517 hospital medical records, 98.3% used two or more drugs, with a single drug accounted for 1.7%. In 24 hours with 2 to 5 kinds of drugs accounted for 48.91%, with 6 to 10 kinds of drugs accounted for 39.55%. Approximately 40% of concurrent drug use cases have beneficial interactions, 20% have adverse interactions, and the remaining 25% have no meaningful drug interactions. Of the 200 hospitalized deaths, 22 (11%) were directly or not excluded from drug-related deaths, most of which were not unconquerable contradictions or unavoidable drug reactions Symptoms and the presence of undesirable drug interactions. Drug-induced deaths, the vast majority of its original disease is more critical and is currently no special treatment of severe diseases, such as cerebrovascular disease, coronary heart disease, significant liver and kidney dysfunction, pulmonary heart disease and cancer. Although there is little hope of cure, it is not unusual for medication errors to promote death. This is absolutely not allowed in medical ethics and medical treatment. Patients with mild and completely original disease can be cured, and the death caused by the wrong medication is rare, it is reported that only occupy the drug extremely