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1 慢性粒细胞白血病慢性粒细胞白血病(Chronic granulocytic leukemia,CGL)是起源于多能造血干细胞的恶性肿瘤病变可累及各种髓系细胞,但以粒细胞特别是中性粒细胞的异常最明显,个别患者还可累及B淋巴细胞,增殖的白血病细胞常有不同程度的成熟障碍.其中大部分尚保持着正常细胞的形态和功能。90％以上的患者骨髓细胞有Ph染色体。体病可发生于各年龄组,以30—40岁者居多.男略多于女.在国内CGL.最常见,约占所有白血病的18％,如果不经有效治疗.诊断后平均生存期约2年。
1 chronic myeloid leukemia chronic granulocytic leukemia (CGL) is a malignant tumor derived from pluripotent hematopoietic stem cell lesions can affect a variety of myeloid cells, but the granulocytes, especially neutrophils, the most obvious abnormalities, Individual patients can also afflict B lymphocytes, proliferating leukemia cells often have varying degrees of maturation disorders. Most of them still maintain normal cell morphology and function. More than 90% of patients have Ph chromosomes in bone marrow cells. Physical illness can occur in all age groups, mostly 30 to 40 years old. Male slightly more than women. In the domestic CGL. The most common, accounting for about 18% of all leukemia, if not treated effectively. The average survival time after diagnosis is about 2 years.