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人工合成的双链核酸聚肌胞(Poly I:C)是一种高效干扰素诱生剂,具有激活天然杀伤细胞,调节免疫机能,促进巨噬细胞吞噬功能等多种生物学效应。近来发现聚肌胞还有活化2′,5′寡聚腺苷酸合成酶和蛋白质激酶的作用。1983年Strander Hans等指出干扰素对小儿咽喉癌、乳头癌、恶性骨瘤及骨髓瘤等有很高疗效,对硬化症、肾癌和恶性淋巴瘤也有效;并指出在临床上应该同时使用干优素及诱生剂等。由于人体血清内有少量的核糖核酸酶
Poly I: C is a kind of highly effective interferon inducer with many biological effects such as activating natural killer cells, regulating immune function and promoting macrophage phagocytosis. It has recently been found that polychaetes also have the effect of activating 2 ’, 5’ oligoadenylate synthase and protein kinases. In 1983, Strander Hans et al. Pointed out that interferon has a high curative effect on children’s throat cancer, papillary carcinoma, malignant osteoma and myeloma, and is also effective on sclerosis, kidney cancer and malignant lymphoma. It is also pointed out that interferon should be used clinically simultaneously Yusu and inducers and so on. Due to the human serum a small amount of ribonuclease