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目的了解和掌握深圳市龙岗区腹泻患者中沙门菌感染状况及菌型分布。方法采集2009-2012年在哨点监测医院(龙岗区人民医院)就诊的腹泻患者粪便标本3 014份,对致病菌进行分离、培养和鉴定,并对阳性菌株进行分子生物学特征分析。结果 3 014份标本共分离到107株沙门菌,阳性率为3.55%,阳性率以10岁以下的年龄组最高;沙门菌的发病率在秋季达高峰,共分离出29种血清型,其中鼠伤寒沙门菌和肠炎沙门菌最多,构成比均占29.7%(各30株)。结论深圳市龙岗区腹泻患者主要以鼠伤寒沙门菌和肠炎沙门菌感染引起的腹泻为主。通过加强对腹泻门诊腹泻患者沙门菌的监测,追踪传播来源,提高暴发流行的预警能力。
Objective To understand and master Salmonella infection and distribution in diarrhea patients in Longgang District, Shenzhen. Methods A total of 3 014 stool samples of diarrhea patients from 2009 to 2012 in the sentinel monitoring hospital (People’s Hospital of Longgang District) were collected for isolation, culture and identification of pathogenic bacteria. Molecular biology characteristics of the positive strains were also analyzed. Results A total of 107 strains of Salmonella were isolated from 3 014 specimens, the positive rate was 3.55%. The positive rate was highest in the age group of 10 years old. The incidence of Salmonella reached its peak in autumn with 29 serotypes isolated. Salmonella typhi and Salmonella enteritidis most, accounting for 29.7% (30 strains each). Conclusion The main diarrhea caused by Salmonella typhimurium and Salmonella enteritidis in patients with diarrhea in Longgang District of Shenzhen City was mainly diarrhea. By strengthening the monitoring of Salmonella in patients with diarrhea outpatient diarrhea, tracking the sources of transmission and improving the early warning capability of outbreaks.