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胰岛素样生长因子 -Ⅰ (ＩＧＦ -Ⅰ )是影响儿童生长发育的重要调控因子 ,它主要是通过生长激素 (ＧＨ) -ＩＧＦ -Ⅰ轴对胎儿的发育及儿童骨骼生长起调节作用。近年来研究发现 ,血液中ＩＧＦ -Ⅰ浓度受到许多因素的影响 ,特别是在儿童严重创伤、感染等情况下其分泌受到明显抑制
Insulin-like growth factor-Ⅰ (IGF-Ⅰ) is an important regulatory factor that affects children’s growth and development. It mainly regulates fetal development and childhood bone growth via growth hormone (GH) -IGF-Ⅰ axis. In recent years, studies have found that blood IGF-Ⅰ concentration by many factors, especially in children with severe trauma, infection and other circumstances were significantly inhibited secretion