在慢性支气管炎的致病因素中,现在一般不包括病毒感染。但当患有病毒感染后,许多研究者均发现慢支急性发作时合并有病毒感染。发生率7～64.3％不等。本文作者观察了111例患者,平均年龄59.19岁,观察时间1～9个月,平均病程7.14±5.01年。在观察期间,44例(39.6％)有1～2次急性发作共49例次。有31例次根据血清学试验及/或病毒分离诊断为病毒感染(63.3％)。29例发作期的不同标本分离到病毒的频率为:单喉拭子—痰液5例;喉拭子—痰液 In the pathogenesis of chronic bronchitis, the virus infection is not normally now included. However, when suffering from a viral infection, many investigators have been found to have a viral infection in the acute episode of chronic bronchitis. The incidence of 7 ~ 64.3%. The authors observed 111 patients with an average age of 59.19 years old, the observation time of 1 to 9 months, an average duration of 7.14 ± 5.11 years. During the observation period, 44 cases (39.6%) had 1 or 2 acute attacks for a total of 49 cases. Thirty-one cases were diagnosed as viral infection based on serological tests and / or virus isolation (63.3%). The frequencies of viruses isolated from 29 different cases of seizures were: single throat swab - sputum 5 cases; throat swab - sputum