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目的探讨健康新生儿血二胺氧化酶(DAO)、D-乳酸的正常含量,为新生儿胃肠功能衰竭的早期诊断寻找可靠的检验依据。方法对79例健康新生儿(足月儿59例,早产儿20例)进行血清DAO、D-乳酸含量测定。结果血清DAO为(8.851±3.424)u/ml,血D-乳酸为(0.918±0.715)ug/ml,血清DAO含量在足月儿与早产儿、在性别之间比较无差异,在日龄之间比较:<3天组与-7天及晚期新生儿各组比较差异无显著性,P值均>0.05,-7天组与晚期新生儿各组比较有显著性差异,P值均<0.05。D-乳酸含量在性别之间差异无显著性(P>0.05),但在早产儿与足月儿、<3d的早期新生儿与>14d的晚期新生儿之间的比较差异有显著性(P<0.05)。结论血DAO不受性别、孕周的影响,血D-乳酸在胎龄、日龄有差别。
Objective To investigate the normal levels of blood diamine oxidase (DAO) and D-lactate in healthy neonates and to find a reliable basis for the early diagnosis of gastrointestinal failure in neonates. Methods Serum DAO and D-lactic acid levels were measured in 79 healthy newborns (59 full-term infants and 20 preterm infants). Results Serum DAO was (8.851 ± 3.424) u / ml and blood D-lactate was (0.918 ± 0.715) ug / ml. There was no difference in DAO between term and preterm infants There was no significant difference between the 3 days group and the -7 days and the late neonates, the P values were all> 0.05. There was significant difference between the -7 days group and the late neonates, P <0.05 . There was no significant difference in D-lactate content between sexes (P> 0.05), but there was significant difference between preterm and full-term infants (P < <0.05). Conclusion Blood DAO is not affected by gender, gestational age, blood D-lactate differences in gestational age, age.