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矽肺是由于含矽粉尘引起的职业病。粉尘进入人体内被吞噬细胞所吞噬。吞噬细胞携带粉尘沿着淋巴管道向肺组织的深部侵入,被吞噬粉尘中的二氧化矽(SiO_2)逐渐溶解于细胞浆中而生成矽酸(H_2SiO_3),由于矽酸的理化学刺激作用而引起肺组织的纤维增生,形成矽结节和间质纤维化。现在一般公认矽肺虽然主要病变多表现在肺部但乃是全身性的疾病。矽肺的病理改变是不可逆的,只要发病以后,即便断绝与粉尘接触,有的亦不能停止其病变发展。在治疗方面,直到目前仍缺乏有效办法。许多学者在这方面曾作过重大的努力,已提出的疗法有铝粉治疗、胰脏素加乳酪、菸硷酸;氧阳压间歇吸入、维
Silicosis is due to occupational diseases caused by silica dust. Dust enters the body and is engulfed by phagocytes. Phagocytic cells carry dust along the lymphatic channels into the deep lung tissue invasion of phagocytic dust in the silicon dioxide (SiO 2) gradually dissolved in the cytoplasm to generate silicic acid (H 2 SiO 3), due to the physicochemical and chemical stimuli of silicic acid caused by the lung Tissue fibrosis, the formation of silicon nodules and interstitial fibrosis. It is now generally recognized that silicosis is a systemic disease although the major lesions are manifested in the lungs. Silicosis pathological changes are irreversible, as long as the onset, even if cut off from contact with dust, and some can not stop the development of its disease. As far as treatment is concerned, there is still no effective solution to this problem. Many scholars have made great efforts in this regard. The treatments that have been proposed include aluminum powder treatment, pancreas plus cheese, nicotinic acid, intermittent inhalation of oxygen pressure,