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神经降压素神经降压素(neurotensin,NT)首次发现是在牛的下丘脑提纯P物质过程中分离出的一种具有扩张血管作用的物质,继后,在牛和人的消化道中也分离出。1973年Carraway和Leeman确定了化学结构,它是由13个氨基酸组成的多肽,分子量为1,673。生物学作用NT具有扩张外周血管的作用,使血压下降。大剂量可使血管通透性增加,血流缓慢,O_2和CO_2交换不足,会出现发绀症状。NT促进ACTH、LH、FSH、GH、催乳素的分泌。NT促进GH和催乳素的分泌可
Neurotensin (NT), the first finding of neurotensin (NT), is a vasodilator substance isolated during the purification of substance P in the hypothalamus of cattle, and subsequently isolated in the digestive tract of cattle and humans Out In 1973 Carraway and Leeman identified the chemical structure, which is a polypeptide of 13 amino acids with a molecular weight of 1,673. The biological role of NT has the role of expanding peripheral blood vessels, blood pressure drops. High-dose vascular permeability can increase, slow blood flow, O_2 and CO_2 exchange deficiencies, there will be symptoms of cyanosis. NT promote ACTH, LH, FSH, GH, prolactin secretion. NT promotes the secretion of GH and prolactin