自1972年起作者采用醋酸正妊娠素(Acétatede Nor-éthistérone)治疗5例严重的全身性硬皮病,结果如下: 例1 女性,37岁,1968年起出现肢端动脉痉挛征。1971年首次检查时,患者全身皮肤发硬,伴明显肢端硬化,手指屈曲性挛缩,指端有溃疡。手活动严重受限,下肢行走不便且伴疼痛。食道受损,心动过速和劳动性呼吸困难。3个月内消瘦7公斤。经各种传统方法治疗无效,应用醋酸正妊娠素后2 Since 1972, the authors used Actetate Nor-éthistérone to treat 5 cases of severe systemic scleroderma. The results were as follows: Example 1 Female, 37 years old, with signs of acral spasm since 1968. The first test in 1971, patients with systemic hardening of the skin, with obvious acromegaly, flexion contracture fingers, finger ulcers. Hand activities are severely limited, lower extremities walking with pain. Esophageal damage, tachycardia and labor difficulty in breathing. 7 months weight loss within 3 months. After a variety of traditional methods of treatment is invalid, the application of positive pregnancy acetate 2