用角膜移植恢复由于角膜变性和营养不良而引起的视力障碍还是一个尚未解决的问题。作者对结节型角膜变性、继发性角膜脂肪变性和有变性的角膜白斑进行了组织病理学、组织化学的检查和临床的观察。(1)结节型角膜变性:作者观察了17例(20眼),大部分病人年龄在30～40岁,男性9人,女性8人。组织病理学的改变主要是不同程度的上皮破坏,Bowman 氏膜消失,在上皮下或实质浅层有无 Corneal transplantation to restore visual impairment due to corneal degeneration and malnutrition remains an open question. The authors of nodular keratosis, secondary corneal steatosis and degeneration of the corneal leukoplakia histopathological, histochemical examination and clinical observation. (1) nodular keratosis: The authors observed 17 cases (20 eyes), most of the patients aged 30 to 40 years old, 9 males and 8 females. Histopathological changes are mainly varying degrees of epithelial damage, Bowman’s membrane disappears, in the subepithelium or in the real shallow presence