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目的分析注射用尿激酶在治疗心源性脑栓塞中的效果。方法 64例心源性脑栓塞患者,随机分为对照组和实验组,各32例。对照组采用控制单一变量的研究方法 ,实验组在对照组的基础上使用注射用尿激酶,对比两组患者在进行治疗后第1、3、5天的神经功能缺损评分(NIHSS)、Barthel指数(BI)量表评定优率以及溶栓后1个月的病死率。结果实验组患者治疗后第1、3、5天的NIHSS评分以及病死率均低于对照组,BI优率高于对照组,差异均具有统计学意义(P<0.05)。结论注射用尿激酶应用于心源性脑栓塞患者的治疗中,能降低患者的NIHSS评分,促进患者神经功能的恢复,降低病死率,有效提高治疗效果,值得应用推广。
Objective To analyze the effect of urokinase for injection in the treatment of cardioembolism. Methods Sixty-four patients with cardiogenic cerebral embolism were randomly divided into control group and experimental group, with 32 cases in each group. In the control group, a single variable-based control method was used. The experimental group used urokinase for injection on the basis of the control group. The NIHSS, Barthel index (BI) scale to assess the rate and 1 month after thrombolysis mortality. Results The NIHSS score and mortality of experimental group were lower than those of control group on the 1st, 3rd and 5th day after treatment, and the BI rate was higher than that of the control group (P <0.05). Conclusion Urokinase used in the treatment of patients with cardiogenic cerebral embolism can reduce the NIHSS score in patients with neurological function to promote recovery, reduce mortality and improve the therapeutic effect, it is worth to promote the application.