论文部分内容阅读
肾素-血管紧张素系统与心血管疾病的发生发展有着复杂而密切的联系。近年来,一种新的血管紧张素转换酶Ⅱ被发现,血管紧张素转换酶Ⅱ的新的代谢通路对肾素-血管紧张素系统传统代谢通路可能有着负性调节作用,它参与了包括血管:紧张素在内的多种肽的代谢过程,在心血管疾病的病理生理方面发挥着重要作用。最近一些研究表明血管紧张素转换酶Ⅱ在动脉粥样硬化发展过程中起到了保护作用,这为动脉粥样硬化和心血管疾病的治疗和预防提供了新的策略。
The renin-angiotensin system has a complex and intimate relationship with the development of cardiovascular disease. In recent years, a new angiotensin converting enzyme II has been found that the new metabolic pathway of angiotensin converting enzyme II may have a negative regulatory effect on the traditional metabolic pathway of the renin-angiotensin system. It is involved in a variety of pathways including blood vessels : The metabolic processes of various peptides, including tocopherol, play an important role in the pathophysiology of cardiovascular disease. Recent studies have shown that angiotensin-converting enzyme Ⅱ plays a protective role in the development of atherosclerosis, which provides a new strategy for the treatment and prevention of atherosclerosis and cardiovascular diseases.