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1983年4月在费城儿童医院召开了人类巨细胞病毒(HCMV)的致病机理与预防会议。虽然有关CMV的分子生物学、致病性及流行病学等问题尚不清楚,但主要的预防对象是宫内和同种异体移植感染患者。人类将研制减毒疫苗和亚单位疫苗以图预防CMV病。现将会议内容概要介绍如下: 自然史美国、英国和瑞典对4万名妇女妊娠感染CMV的作用进行前瞻性研究,为该病毒作为胎儿病原提供了进一步的资料。血清流
April 1983 in Philadelphia Children’s Hospital held a human cytomegalovirus (HCMV) pathogenesis and prevention meeting. Although the molecular biology, pathogenicity, and epidemiology of CMV are not clear, the main prophylaxis is intrauterine and allograft infections. Humans will develop attenuated vaccines and subunit vaccines to prevent CMV disease. The meeting is summarized as follows: Natural History The United States, the United Kingdom and Sweden conducted a prospective study of the pregnancy-induced CMV infection in 40,000 women and provided further information on the virus as a fetal pathogen. Serum flow