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目的:观察地诺前列酮栓应用于足月胎膜早破引产的效果。方法:选择足月(≥37周)胎膜早破178例,随机分为观察组85例和对照组93例。观察组采用地诺前列腺酮栓剂,常规消毒外阴阴道后横置于后穹窿处,临产后取出;对照组采用常规缩宫素2.5U加5%葡萄糖注射液500ml静脉滴注。比较两组临产时间、产程时限、用药后12h宫颈Bishop评分改善及剖宫产情况。结果:观察组用药后临产时间、产程时限均非常显著短于对照组(P<0.01),用药后12h宫颈Bishop评分提高≥3分(包括已分娩)者非常显著多于对照组(P<0.01),行剖宫产者显著少于对照组(P<0.05)。结论:地诺前列腺酮栓应用于足月胎膜早破引产效果较好。
Objective: To observe the effect of dinoprostone suppository on term premature rupture of membranes induced by labor. Methods: 178 cases of full-term premature rupture of membranes (≥37 weeks) were randomly divided into observation group (85 cases) and control group (93 cases). The observation group was treated with diolaprost suppository, and the vagina was routinely disinfected. The vagina was transversely placed at the posterior fornix and taken out after labor. The control group was treated with conventional oxytocin 2.5U plus 500ml dextrose 500ml intravenously. The duration of labor, the duration of labor and the improvement of cervical Bishop score and cesarean section at 12h after treatment were compared between the two groups. Results: The duration of labor and the duration of labor were significantly shorter in the observation group than in the control group (P <0.01), and the Bishop score ≥3 (including delivered) at 12h after treatment was significantly higher than that of the control group (P <0.01) ), Cesarean section was significantly less than the control group (P <0.05). Conclusion: Connaught prostatic ketosis suppository for premature rupture of membranes induced labor is better.