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近几年来国内外应用利福平治疗麻风病的报道日渐增多,较多学者认为疗效较好,但也有一些学者认为疗效并不满意,争论颇大。自八○年十月我们利用未曾服过抗麻风药的病人,给予一次剂量1500毫克利福平(罗马利亚进口)服用后,分次将患者皮肤活体组织的细菌接种于鼠足垫上,观察细菌的生长情况,评价药物疗效,现将详细情况报告如下: 一、实验方法 1.实验病人:新入院的麻风患者(病人情况见表一)在未服利福平时,便取其皮肤活体组织的细菌接种在小白鼠足垫上,然后给于1500毫克的利福平一次服下,随后三
In recent years, the domestic and international application of rifampicin treatment of leprosy reports increasing, more scholars believe that the curative effect is better, but some scholars think the curative effect is not satisfied, the debate is quite large. Since October 1980, we took a dose of 1500 mg of rifampicin (imported from Romania) on patients who had not been given anti-leprosy medicine and inoculated bacteria on skin of patient’s skin in several batches to observe bacteria Of the situation, the evaluation of the efficacy of the drug, the details of the report are as follows: First, the experimental method 1. Experimental patients: new patients admitted to leprosy (patients see Table I) did not take rifampin, they take the skin of living tissue Bacteria were inoculated on foot pads in mice and then given once to 1500 mg of rifampicin, followed by three