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本研究应用Ｈ２Ｏ２蒸气（５．４，３２．１ｍｇ／ｍ３）进行大鼠亚急性吸入染毒。大鼠吸入Ｈ２Ｏ２蒸气后，发现血清ＡＫＰ和ＡＣＰ活性增高，全血ＣＡＴ及肺组织ＳＤＨ活性降低。同时还发现肺组织ＧＳＨ含量明显降低，ＭＤＡ含量显著升高。Ｈ２Ｏ２对呼吸系统不仅有刺激作用还可诱发对肺脏的氧化性损伤。
In this study, sub-acute inhalation of rats was performed using H2O2 vapor (5.4, 32.1 mg / m3). Rat inhaled H2O2 vapor, found that serum AKP and ACP activity increased, whole blood CAT and lung tissue SDH activity decreased. Also found that the content of GSH in lung tissue decreased significantly, MDA content increased significantly. H2O2 not only stimulates the respiratory system but also induces oxidative damage to the lungs.