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目的:探讨以冷冻为主综合治疗肝癌的疗效。方法:应用LSC-2000型冷冻机对53例肝癌分别采取冷冻加手术切除;冷冻加肝动脉、门静脉置管化疗;冷冻加手术切除和肝动脉、门静脉置管化疗。结果:全组无手术死亡及严重并发症;冷冻后1、2年和3年生存率分别为73.6％、62.5％和52.8％,其中12例≤5mm的小肝癌分别91.7％、83.3％和75％。结论:冷冻综合治疗为中、晚期肝癌提供了一个有效的治疗途径;冷冻后切除肿瘤或/和行肝动脉、门静脉置管化疗能够降低肝癌术后的复发率。
Objective: To explore the comprehensive treatment of liver cancer with freezing effect. Methods: Fifty-three cases of HCC were treated by LSC-2000 freezer plus resection, frozen-thawed hepatic artery and portal vein catheterized chemotherapy, combined with surgical resection and hepatic artery and portal vein catheterization chemotherapy respectively. Results: There was no operative mortality and serious complications in the whole group. The 1, 2 and 3 year survival rates were 73.6%, 62.5% and 52.8%, respectively. Of these, 12 cases of small hepatocellular carcinoma ≤5 mm were 91.7%, 83.3% and 75% %. Conclusion: The combined treatment of freezing and thawing can provide an effective treatment for advanced hepatocellular carcinoma. After resection of the tumor or / and the treatment of hepatic artery and portal vein catheterization can reduce the postoperative recurrence rate of liver cancer.