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内皮细胞不仅是血液与组织间液之间的屏障,而且具有广泛的代谢功能,从而调节肺血管张力及对缺氧的反应性。前列环素(PGI_2)和血栓素A_2(TXA_2)在内皮细胞内的代谢非常活跃,在缺氧性肺血管收缩反应(HPV)中起重要作用。吸烟是慢性肺心病和肺动脉高压的主要病因之一。有研究表
Endothelial cells are not only a barrier between blood and interstitial fluid, but also have a wide range of metabolic functions that regulate pulmonary vascular tone and hypoxia response. The metabolism of PGI_2 and TXA_2 in endothelial cells is very active and plays an important role in hypoxic pulmonary vasoconstriction (HPV). Smoking is one of the major causes of chronic pulmonary heart disease and pulmonary hypertension. A research table