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引言血尿的诊断,特别在无肾脏或系统性疾病证据的患者仍是一个难题。原发性血尿病人肾活检近22%的成人和44%的儿童可正常。尽管有许多报告用位相显微镜能区别肾小球性出血和其他原因所致的血尿,肾小球性红细胞(RBC)有畸变,而非肾小球性RBC与外周RBC非常相似,然而位相显微镜检的敏感性和特异性已引起高度怀疑。作者曾介绍过一种检测异常尿RBC形态的新方法,即利用自动血细胞分析仪获得容积分布曲线,可避免对畸变RBC程度和频率的主观臆断,由于能够进行大量尿RBC计数和易于即刻测量,RBC的形态学就能与病因疾患相关联。作者对上法进行了改进,
Introduction The diagnosis of hematuria, especially in patients with no evidence of kidney disease or systemic disease, remains a challenge. Nearly 22% of adults with renal biopsy and 44% of children with primary hematuria may be normal. Although there are many reports that use phase microscopes to differentiate between hematuria due to glomerulonephritis and other causes, the presence of aberrant glomerular erythrocytes (RBCs), rather than glomerular RBCs, is very similar to peripheral RBCs, however, phase microscopy The sensitivity and specificity have caused high suspicion. The authors have introduced a new method to detect the abnormal morphology of RBC in urine by using the automatic hematology analyzer to obtain the volume distribution curve to avoid the subjective assumption of the degree and frequency of distorted RBC due to the large number of urine RBC counts and easy immediate measurement, RBC morphology can be associated with etiology. The author made improvements to the law,