The hypoxia inducible factors(Hifs) are evolutionarily conserved transcriptional factors that control homeostatic responses to low oxygen. In developing bone, H
Although insulin-like growth factor-I(IGF-I) and estrogen signaling pathways have been shown to be involved in mediating the bone anabolic response to mechanica
Daily 20-mg and once-weekly 56.5-mg teriparatide(parathyroid hormone 1–34) treatment regimens increase bone mineral density(BMD) and prevent fractures, but cha