抗精神药物引起恶性症状群已为人所熟知。抗抑郁剂引起恶性症状群的报告不多,除1例单用氨苯甲异喹报告外,余为合并用药所致,本文报告1例单用氯丙咪嗪静注发生恶性症状群。患者,男性,45岁。过去曾两次患抑郁症,经抗抑郁治疗而缓解。79年9月,发现学生作弊,未向校方报告,担心被校方发现 The group of anti-psychotic drugs that cause malignant symptoms is well known. Antidepressants caused by malignant symptoms of small group report, except for 1 case of single report of anisidine, more than due to combination therapy, this report reported a single intravenous injection of clomipramine malignant symptoms group. Patient, male, 45 years old. In the past twice had depression, relieved by antidepressant treatment. September 79, found that students cheating, did not report to the school, fear of being discovered by the school