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0 引言 人类腭裂与小鼠腭裂在形态发生上十分相似 .目前 ,其中致畸率最高的是 C5 7BL / 6 N系小鼠腭裂模型 [1 ] .但国内尚未见到成功的报道 .本研究采用 C5 7BL/ 6 N系小鼠管饲维甲酸 (retionic acid,RA) ,建立了稳定的腭裂动物模型 .1 材料和方法1.1 材料 C5 7BL/ 6 N
0 Introduction Human cleft palate and mouse cleft palate morphology is very similar at present, the highest rate of teratogenicity is the C5 7BL / 6 N mouse cleft palate model [1], but the country has not yet seen the success of the report in this study C5 (7BL / 6) N mice were fed with retionic acid (RA) to establish a stable animal model of cleft palate.1 Materials and Methods 1.1 Materials C5 7BL / 6 N