论文部分内容阅读
目的探讨心肌损伤标志物联合检测在急性心肌梗死(acute myocardial infarction,AMI)诊断中的应用。方法对在本院接受诊断与治疗的急性心肌梗死患者进行心肌损伤标志物联合检测。结果发病2 hAMI组与对照组比较,Myo差异有统计学意义(P<0.05);发病4 h AMI组与对照组比较,Myo、CK-MB差异有统计学意义(P<0.05);发病8 h AMI组与对照组比较,Myo、CK-MB、cTnI差异有统计学意义(P<0.05)。cTnI+Myo+CK-MB 2项或3项联合检测,更能提高特异性,cTnI+Myo+CK-MB在发病4 h的敏感性和特异性分别是44.26%(27/61),90.16%(55/61),发病8 h的敏感性和特异性均为100%,具有很高的诊断率。结论联合监测Myo、cTnI、CK-MB可提高对AMI诊断的敏感性和特异性,同时对再梗死发生、预后及观察疗效具有重要意义。
Objective To investigate the application of combined detection of myocardial injury markers in the diagnosis of acute myocardial infarction (AMI). Methods Combined detection of myocardial injury markers in patients with acute myocardial infarction undergoing diagnosis and treatment in our hospital. Results There was a significant difference in Myo between the 2-h AMI group and the control group (P <0.05). There were significant differences in Myo and CK-MB between the AMI group and the control group 4 h after onset (P <0.05) h AMI group compared with the control group, Myo, CK-MB, cTnI difference was statistically significant (P <0.05). The sensitivity and specificity of cTnI + Myo + CK-MB were 44.26% (27/61) and 90.16% respectively at the onset of 4 h after cTnI + Myo + CK-MB 2 or 3 combined detection. (55/61). The sensitivity and specificity of the 8 h onset were 100%, with a high diagnostic rate. Conclusions The combined monitoring of Myo, cTnI and CK-MB can improve the sensitivity and specificity of AMI diagnosis, and is of great significance for the occurrence, prognosis and observation of the curative effect of reinfarction.