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目的:了解丽水市5岁以下腹泻婴幼儿粪便A群轮状病毒(RV)感染情况,为临床诊断和治疗提供可靠依据。方法:采用胶体金法对2010年3月-2011年2月来我院就诊的3373例腹泻患儿的粪便标本进行RV抗原检测,并比较检测结果。结果:3373例腹泻标本中有982例RV结果阳性,阳性率为29.1%,其中6个月～1岁及1岁～2岁幼儿是轮状病毒感染的高发年龄段,检测阳性率分别为31.6%和35.9%。轮状病毒腹泻发病的高峰季节是10月份至次年的2月份。结论:轮状病毒感染是导致婴幼儿腹泻的主要原因之一,以6个月至2岁组为A群轮状病毒的高发年龄组,每年的10月至次年的2月为感染高峰期,临床医生应重视腹泻病原的检测,以明确诊断,防止滥用抗生素而导致肠道菌群失调,使腹泻迁延不愈。
Objective: To understand the infection status of Rotavirus A (RV) in infants and young children with diarrhea under 5 years of age in Lishui City, and provide a reliable basis for clinical diagnosis and treatment. Methods: RV antigen was detected by colloidal gold assay in 3373 cases of diarrhea in our hospital from March 2010 to February 2011, and the test results were compared. Results: Among the 3373 cases of diarrhea, 982 cases were positive for RV, with a positive rate of 29.1%. Among them, 6 months to 1 year old children and 1 to 2 years old children were the highest incidence of rotavirus infection. The detection positive rates were 31.6 % And 35.9%. The peak season for the onset of rotavirus diarrhea is from October to February of the following year. CONCLUSIONS: Rotavirus infection is one of the major causes of diarrhea in infants and young children. It ranges from 6 months to 2 years old as group A rotavirus. The peak period of infection is from October to the next February , Clinicians should pay attention to the detection of diarrhea pathogens in order to confirm the diagnosis, prevent the abuse of antibiotics and lead to intestinal flora disorders, delayed healing of diarrhea.