目的探讨老年消化性溃疡（ＰＵＡ）的临床及内镜下特点．方法１９８５－１９９４年６０岁以上消化性溃疡（ＰＵ）住院患者２２２例，以同期６０岁以下ＰＵ１００例为对照进行临床内镜分析．结果老年胃溃疡占同期胃溃疡住院人数的构成比已由１９８５年的１０９％递增至１９９４年的２４０％．ＰＵＡ上腹痛、节律性腹痛、反酸、烧心症状发生率依次为５７８％，２２５％，３１５％和１０４％，对照组依次为８７０％，４５０％，４８０％和３８０％（Ｐ＜００１）．并发症发生率ＰＵＡ组为６０８％，对照组为４００％（Ｐ＜００１）．ＰＵＡ直径大于３ｃｍ者占２２５％，对照组为４０％（Ｐ＜００１）．行手术治疗者ＰＵＡ组为２１６％，对照组为１１０％（Ｐ＜００１）．结论ＰＵＡ临床症状不典型，并发症发生率高，巨大溃疡常见，出血难止，手术机率增加 Objective To investigate the clinical and endoscopic features of senile peptic ulcer (PUA). Methods A total of 222 inpatients with peptic ulcer (PU) over the age of 60 from 1985 to 1994 were enrolled in this study. Results The proportion of senile gastric ulcer to the number of hospitalized patients with gastric ulcer in the same period increased from 10.9% in 1985 to 24.0% in 1994. The rates of abdominal pain, rhythm abdominal pain, acid reflux and heartburn symptoms were 578%, 225%, 315% and 104% in PUA, 870% and 450% in control group, , 480% and 380% (P <001). Complication rate was 608% in PUA group and 400% in control group (P <001). PUA diameter greater than 3cm accounted for 22  5%, the control group was 4  0% (P <0  01). The surgical treatment group was 21.6% in the PUA group and 11.0% in the control group (P <001). Conclusions The clinical symptoms of PUA are not typical, the incidence of complications is high, the huge ulcer is common, the bleeding is difficult and the chance of operation is increased