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目的探讨三阴乳腺癌病理分期病理分级与预后的关系。方法选取2007年1月至2010年12月间四川省人民医院收治的71例三阴乳腺癌患者,观察终点为患者乳腺癌复发或转移,分析患者预后与T分期、N分期及分级的关系。结果 14例患者出现复发转移,三阴乳腺癌患者随着T分期增加,复发转移概率,差异无统计学意义(P>0.05);当N分期为N2或以上时,复发转移概率明显增加,差异有统计学意义(P<0.05);病理G分级与三阴乳腺癌无明显关系,差异无统计学意义(P>0.05)。结论三阴乳腺癌随N分期增加预后变差,早发现对于提高治疗效果非常重要。
Objective To investigate the relationship between pathological grade and prognosis of triple-negative breast cancer. Methods A total of 71 patients with triple-negative breast cancer who were treated in Sichuan Provincial People’s Hospital from January 2007 to December 2010 were recruited. The patients were followed up for recurrence or metastasis. The relationship between prognosis and T stage, N stage and grade was analyzed. Results The recurrence and metastasis were found in 14 patients. There was no significant difference in recurrence and metastasis with the increase of T stage and T stage in patients with triple negative breast cancer (P> 0.05). When the N stage was N2 or above, the recurrence and metastasis probability was significantly increased, (P <0.05). There was no significant correlation between pathological G grade and triple-negative breast cancer (P> 0.05). Conclusion The prognosis of triple negative breast cancer with the increase of N stage is poor. Early detection is very important for improving the therapeutic effect.