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本研究应用中药心肌康对左心室肥厚(LVH)患者进行逆转性治疗。94例LVH患者随机分为心肌康治疗组(74例)和美多心安对照组(20例),作服药前后的临床疗效观察。结果表明:心肌康对LVH有显著的退缩作用(P<0.05,P<0.01),对照组对LVH的治疗虽有一定程度的改善,但无统计学意义,两组于治疗后比较亦呈显著性差异(P<0.01)。心肌康对LVH的病因具有缓解或消除的作用,如心功能和微循环的改善,血粘度、血载脂蛋白A-1(APOA-1)、心肌耗氧量(RPP)的降低和超氧化物歧化酶(SOD)升高等,治疗前后均有显著性差异,与对照组比较,亦具有统计学意义(P<0.05或P<0.01)。上述结果提示心肌康对LVH具有一定的逆转作用。
In this study, the application of traditional Chinese medicine IKK on patients with left ventricular hypertrophy (LVH) reversal treatment. Ninety-four patients with LVH were randomly divided into two groups, namely, Xinjikang group (74 cases) and Metoprolol group (20 cases) for clinical observation. The results showed that: myocardial glycogen significantly retarded LVH (P <0.05, P <0.01), while the control group for the treatment of LVH although some degree of improvement, but no statistical significance, both groups after treatment Comparison also showed significant difference (P <0.01). Myocardial health effects of LVH eased or eased, such as improvement of cardiac function and microcirculation, blood viscosity, apolipoprotein A-1 (APOA-1), myocardial oxygen consumption (RPP) decreased and superoxide Compared with the control group, there was also a significant difference between before and after treatment (P <0.05 or P <0.01). The above results suggest that myocardial Kang has a certain reversal of LVH.