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愈来愈多的证据表明钙通道阻滞剂硝苯啶除有益于心绞痛外,对治疗慢性原发性高血压和高血压急症亦有效.本文综述这方面的资料.临床研究1976年Aloki等首先证实舌下含服硝苯啶对治疗因恶性高血压、肾动脉狭窄和原发性醛固酮增多症所致的高血压急症有效,收缩压(SBP)降低30%,舒张压(DBP)降低26%,平均压(?)降低28%,服后15分钟生效,作用持续4小时.此后陆续有21位作者
There is increasing evidence that nifedipine, a calcium channel blocker, is also useful in the treatment of chronic essential hypertension and acute hypertension in addition to its beneficial effects on angina pectoris. This article reviews data in this regard. Clinical Studies 1976 Aloki et al. Sublingual nifedipine was shown to be effective in the treatment of hypertensive emergencies due to malignant hypertension, renal artery stenosis and primary aldosteronism with a 30% reduction in systolic blood pressure (SBP) and a 26% reduction in diastolic blood pressure (DBP) , The average pressure (?) Decreased by 28%, 15 minutes after taking effect, the role lasts 4 hours after another 21 authors