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作者报道用免疫血清球蛋白(ISG)预防输血后非甲非乙型肝炎的结果。将291例随机接受供血者血液的心脏手术患者分为两组。143例患者于输血前和输血后1周肌肉注射市售16%ISG溶液10ml,未注射SIG的148例患者为对照组。输血前、手术后2～4周以及此后至少180天内每月采集血清1次。如发现丙氨酸转氨酶(ALT)水平持续升高继续随访。检测所有血清的HBsAg、抗-HBs、抗-HBc、甲型肝炎病毒抗体(抗-HAV)、ACT、天门冬氨酸转氨酶(AST)、直接胆红素和总胆红素水平。此外,当患者罹患肝炎时,检查抗-HBc
The authors report the results of using immunoglobulin (ISG) to prevent non-A, non-B hepatitis after transfusion. 291 patients randomized to receive donor blood were divided into two groups. 143 patients were intramuscularly injected with 10 ml of commercially available 16% ISG solution before transfusion and 1 week after transfusion, and 148 controls without SIG. Serum was collected monthly before blood transfusion, 2 to 4 weeks after surgery, and at least 180 days thereafter. If found in alanine aminotransferase (ALT) levels continued to follow up. Anti-HBs, anti-HBc, anti-Hepatitis A virus (anti-HAV), ACT, aspartate aminotransferase (AST), direct bilirubin and total bilirubin levels were measured in all sera. In addition, anti-HBc is examined when the patient is suffering from hepatitis