例1:患儿女,1岁,因头疼发烧1天,呕吐10余次,继之神志不清,以流脑收住入院。查体:体温37℃,脉搏146次/分,血压(12/8kPa),面色苍白,四肢冰冷,神志模糊、烦躁、前囟饱满、全身皮肤散在出血点和瘀斑,瘀斑为0.4～2cm~2不等10余处,瞳孔等大,光反射正常,颈抗、心律正,无杂音。布氏征(+),克氏征(+)。化验:白细胞 Example 1: Children, 1 year old, have a fever for one day because of a headache and vomited for more than 10 times, followed by unconsciousness and admitted to hospital with mecca. Physical examination: body temperature 37 ℃, pulse 146 beats / min, blood pressure (12 / 8kPa), pale, cold limbs, confusion, irritability, full of anterior fontanelle, the whole body scattered bleeding spots and ecchymosis, ecchymosis 0.4 ~ 2cm ~ 2 ranging from more than 10 Department, such as large pupils, light reflex normal, cervical anti-rhythm, no noise. Brinell sign (+), Kirschner sign (+). Laboratory: white blood cells