论文部分内容阅读
目的探讨青年妇女发生宫颈癌的独立危险因素及预后情况。方法回顾性分析2010年10月-2013年3月于该院就诊的126例确诊为宫颈癌患者的临床资料,根据患者年龄将其分成青年组42例和中老年组84例。对比两组患者一般资料差异,对单因素分析后差异有统计学意义的指标行非条件Logistic回归分析;行为期3年随访,记录两组患者生存率及复发率差异。结果 1青年组性伴侣个数超过2个、长期吸烟史患者例数均显著多于中老年组,差异有统计学意义(P<0.05);中老年组妊娠次数超过3次者显著多于青年组,差异有统计学意义(P<0.05);青年组工具避孕率及药物避孕率均明显高于中老年组,而中老年组的节育手术避孕率显著高于青年组,差异有统计学意义(P<0.05);2非条件Logistic回归分析显示,长期吸烟史及性伴侣人数是青年妇女发生宫颈癌的独立危险因素,均同宫颈癌的发生呈正相关性(P<0.05);3青年组3年内死亡率为47.6%(20/42),复发率为33.3%(14/42),均显著高于中老年组的29.8%(25/84)和16.7%(14/84),差异有统计学意义(P<0.05)。结论性伴侣超过2个、长期吸烟等是青年妇女发生宫颈癌的独立危险因素;青年宫颈癌妇女3年内死亡率及复发率较高,预后水平较差,需引起临床重视。
Objective To investigate the independent risk factors and prognosis of young women with cervical cancer. Methods A retrospective analysis of clinical data of 126 cases diagnosed as cervical cancer from October 2010 to March 2013 in our hospital was made. According to the age of the patients, 42 cases were divided into young group and 84 middle aged group. The differences of general data between the two groups of patients were compared. The univariate logistic regression analysis was used to analyze the differences between the two groups. The 3-year follow-up was performed to record the difference of survival rate and recurrence rate between the two groups. Results There were more than 2 sexual partners in the youth group, and the number of long-term smoking history patients was significantly higher than that in the middle-aged and elderly groups (P <0.05). In the middle-aged and elderly groups, the number of pregnancy was significantly higher than that in the youth Group, the difference was statistically significant (P <0.05); young people contraceptive rate of contraceptives and drugs were significantly higher than the middle-aged group, contraception rate of birth control surgery in the middle-aged group was significantly higher than the youth group, the difference was statistically significant (P <0.05) .2 Non-conditional Logistic regression analysis showed that long-term smoking history and the number of sexual partners were independent risk factors for cervical cancer in young women, which were positively correlated with the occurrence of cervical cancer (P <0.05) The 3-year mortality rate was 47.6% (20/42) and the recurrence rate was 33.3% (14/42), which were significantly higher than 29.8% (25/84) and 16.7% (14/84) in middle-aged and elderly patients, respectively Statistical significance (P <0.05). Conclusions More than 2 sexual partners and long-term smoking are independent risk factors for cervical cancer in young women. Youth women with cervical cancer have a higher mortality and relapse rate within 3 years and a worse prognosis, which needs clinical attention.