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已有研究表明贲门失弛缓症患者有食管以外的消化道动力异常。本研究对１０例贲门失弛缓症和１０例性别年龄均可比的健康志愿者，进行了胃十二指肠测压以及血胃泌素和血管活性肠肽的放免测定。结果显示，二组胃窦、十二指肠近、远瑞消化间期移行性运动复合波（ＭＭＣ）Ⅰ、Ⅱ、Ⅲ期的时间比、ＭＭＣⅡ、Ⅲ期收缩次数、收缩振幅及动力指数均差异无显著性；而胃泌素及ＶＩＰ水平亦在正常范围。研究表明，本组贲门失弛缓症的神经受损未影响胃窦和十二指肠的消化间期运动，血胃泌素、ＶＩＰ释放不受影响。
Studies have shown that patients with achalasia gastrointestinal motility esophageal abnormalities. In this study, 10 volunteers with cardiac achalasia and 10 gender-age-matched healthy volunteers were enrolled in this study. Gastroduodenal manometry and radioimmunoassay of blood gastrin and vasoactive intestinal peptide were performed. The results showed that the time ratio of stage Ⅰ, Ⅱ and Ⅲ of MMC in gastric antrum and proximal duodenum to distal rehilagation, MMC Ⅱ and Ⅲ contractions, systolic amplitude and dynamic index No significant difference; while gastrin and VIP levels are also in the normal range. Studies have shown that this group of cardiac achalasia neurological damage did not affect the gastric antrum and duodenal interdigestive motility, blood gastrin, VIP release is not affected.