Objective: To find herbs with effects on adhesion and migration of melanocytes in vitro. Materials and Methods: Ethanol extracts from 14 herbs were tested. Normal human melanocytes were obtained from neonatal foreskin, and the 48-well culture dish covered with fibronectin was used for the melanocyte adhesion assay. Motility was assessed by using the micropore filter method. Results: The extracts of could promote both adhesion and migration of melanocytes. Conclusion: The above herbs may play a role through promoting adhesion and/or migration of melanocytes in the treatment of vitiligo.