论文部分内容阅读
本文报告未净化自体骨髓移植(ABMT)17例,净化自体骨髓移植(PABMT)30例,自体外周血干细胞移植48例),男61例,女34例,中位年龄27岁(3.7～47岁),急性髓细胞性白血病(AML)58例,急性淋巴细胞性白血病(ALL)35例,慢性粒细胞白血病(CML)2例.移植时第1次缓解(CRl)72例,第2次缓解(CR2)22例,未缓解(NR)1冽,缓解(CR)到移植的时间中位数7个月(2～19月).骨髓净化方法:胎肝低分子抑物净化,长期体外液体培养净化及癌光啉加光照净化.移植前经强烈的化疗和全身放疗(TBI)后移植.ABMT组、PABMT组、APBHSCT组3年无病生存率(DFS)及复发率分别为64.8%,73.4%,70.5%和35.2% ,26.6%,29.5%.造
This article reports 17 untreated bone marrow transplants (ABMT), 30 autologous bone marrow transplants (PABMT), 48 autologous peripheral blood stem cell transplants, 61 males and 34 females, with a median age of 27 years (3.7 to 47 years). ), 58 cases of acute myeloid leukemia (AML), 35 cases of acute lymphocytic leukemia (ALL), and 2 cases of chronic myeloid leukemia (CML). 72 cases of the first remission (CRl) at the time of transplantation, the second remission (CR2) 22 cases, non-remission (NR) 1 冽, median time to relief (CR) to transplantation 7 months (2 to 19 months). Bone marrow purification method: fetal liver low molecular inhibitor purification, long-term in vitro liquid Culture and purification, plus cancer photorinma plus light purification. Before transplantation, after intense chemotherapy and systemic radiation (TBI) transplantation, ABMT group, PABMT group, APBHSCT group 3-year disease-free survival rate (DFS) and recurrence rate was 64.8%, 73.4%, 70.5% and 35.2%, 26.6%, 29.5%.