盐酸甲氧氯普胺是一种能镇静神经的多巴胺受体拮抗剂,常用于治疗胃病.据报道它能引起锥体外运动障碍.本文研究的目的是:①确定使用甲氧氯普胺治疗的患者中,导致迟发性运动障碍以及急性锥体外综合征包括静坐不能、急性肌张力障碍和药物性帕金森综合征的发生率及严重度;②比较糖尿病患者和非糖尿病患者使甲氧氯普胺治疗时引起迟发性运动障碍的发生率及严重度. Metoclopramide hydrochloride is a neurotrophic dopamine receptor antagonist commonly used in the treatment of gastric disorders and is reported to cause extrapyramidal motility disorders.The purpose of this study was to determine whether metoclopramine-treated Patients, leading to tardive dyskinesia and acute extrapyramidal syndrome, including seizures, acute dystonia and drug-induced Parkinson’s disease incidence and severity; ② comparison of diabetic and non-diabetic patients with metoclop The incidence and severity of tardive dyskinesia caused by amine treatment.