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Objective:To evaluate whether radiofrequency ablation(RFA) might have an influence on immune status in hepatocellular carcinoma(HCC) patients. Methods:We measured the T lymphocytes,B lymphocyte and NK cells,and determined the population of Th1, Th2,Tc1 and Tc2 of peripheral blood samples taken from 26 HCC patients before and after RFA. Results:The proportion of Type1 cells(Th1 and Tc1) and NK cells were significantly increased after RFA, especially in patients of the following subgroups:male,age>55 years,pathological gradeⅠ-Ⅱtumor,clinical stageⅠ-Ⅱor Child-Pugh A and B. Conclusion:Type1 cells and NK cells in HCC patients were increased in a short period after RFA.
Objective: To evaluate whether radiofrequency ablation (RFA) might have an influence on immune status in hepatocellular carcinoma (HCC) patients. Methods: We measured the T lymphocytes, B lymphocyte and NK cells, and determined the population of Th1, Th2, Tc1 and Tc2 of peripheral blood samples taken from 26 HCC patients before and after RFA. Results: The proportion of Type 1 cells (Th1 and Tc1) and NK cells were significantly increased after RFA, especially in patients of the following subgroups: male, age> 55 years , pathological grade I-II tumor, clinical stage I-II Child-Pugh A and B. Conclusion: Type 1 cells and NK cells in HCC patients were increased in a short period after RFA.