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为观察抗中性粒细胞胞浆抗体（ANCA）在不同肾小球疾病中的发生率及临床意义，用间接免疫荧光法检测180例患儿血清ANCA≥1：20者为阳性，并作肾活检病理检查。结果180例中24例ANCA阳性（13．3％）。各病阳性率6．2％～100％。ANCA持续时间平均3mo。认为ANCA除为原发性血管炎重要诊断依据外，亦见于其他肾小球疾病，特别对急进性肾炎、狼疮肾炎及紫癜性肾炎的诊断有参考价值。
To observe the incidence of anti-neutrophil cytoplasmic antibodies (ANCA) in different glomerular diseases and its clinical significance, indirect immunofluorescence was used to detect the serum ANCA≥1: 20 in 180 children as positive and kidney Biopsy pathology. Results Of the 180 cases, 24 were ANCA positive (13.3%). The positive rate of each disease 6.2% ~ 100%. ANCA duration of an average of 3mo. That ANCA addition to the important basis for the diagnosis of primary vasculitis, but also found in other glomerular diseases, especially for the diagnosis of acute nephritis, lupus nephritis and purpuric nephritis have reference value.