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目的：探讨小儿腹痛与小儿慢性胃十二指肠疾病的关系。方法：对５９３例具有复发性腹痛症状的２岁９月～１４岁小儿进行胃镜检查，其中２６４例同时取胃粘膜进行组织学检查。结果：胃镜检查为胃十二指肠疾病的阳性率为８５．２％（５０５／５９３）。其慢性胃炎、慢性胃炎并十二指肠炎、十二指肠炎、十二指肠球部溃疡、胃溃疡的阳性率分别为２９．０％（１７２／５９３），２３．１％（１３７／５９３），２２．１％（１３１／５９３），９．５（５６/５９３），１．５％（９/５９３）。病理检查幽门螺杆菌（ＨＰ）阳性率为 ２９．ｌ％（７７/２６４）。组织学检查为固有层淋巴细胞和浆细胞浸润，多形白细胞浸润较少，与成人ＨＰ感染胃粘膜组织学明显不同。结论：慢性胃十二指肠疾病是引起小儿腹痛常见的主要原因之一。ＨＰ感染病理改变全部表现为慢性幽门螺杆菌性胃炎。
Objective: To investigate the relationship between pediatric abdominal pain and chronic gastroduodenal diseases in children. Methods: Gastroscopy was performed on 593 children aged 2 to 9 years old with recurrent abdominal pain. Among them, 264 cases were simultaneously taken gastric mucosa for histological examination. Results: The positive rate of gastroscopy for gastroduodenal disease was 85.2% (505/593). The positive rate of chronic gastritis, chronic gastritis and duodenitis, duodenitis, duodenal ulcer and gastric ulcer were 29.0% (172/593), 23.1% (137/593 ), 22.1% (131/593), 9.5 (56/593), 1.5% (9/593). Pathological examination Helicobacter pylori (HP) positive rate of 29. l% (77/264). Histological examination of lamina propria lymphocytes and plasma cells infiltration, polymorphonuclear leukocyte infiltration less, and adult HP infection gastric mucosa histology was significantly different. Conclusion: Chronic gastroduodenal disease is one of the common causes of abdominal pain in children. Pathological changes of HP infection all showed chronic Helicobacter pylori gastritis.